Skip Navigation

This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Search for citing articles in:
ISI Web of Science (30)
Right arrowRequest Permissions
Right arrow Disclaimer
Google Scholar
Right arrow Articles by Copeland, D. R.
Right arrow Articles by Judd, B. W.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Copeland, D. R.
Right arrow Articles by Judd, B. W.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

Journal of Pediatric Psychology 13(2) pp. 183-196, 1988
© 1988 Society of Pediatric Psychology

research-article

Neuropsychological Test Performance of Pediatric Cancer Patients at Diagnosis and One Year Later1

Donna R. Copeland4, Richard E. Dowell, Jack M. Fletcher, jr2, Margaret P. Sullivan, Norman Jaffe, Ayten Cangir, Lawrence S. Frankel3 and Brian W. Judd

The University of Texas M. D. Anderson Cancer Center Houston, Texas

4All correspondence should be sent to Donna R. Copeland, Department of Pediatrics, TheUniversity of Texas M. D. Anderson Hospital, 1515 Holcombe, Houston, Texas 77030

More children with cancer are surviving, and the effects of medical treatments are of interest to patients, parents, educators, and the treatment team, since results may influence further treatment planning and delivery of educational services. Longitudinal investigations employing baseline measures are essential to distinguish preexisting learning problems from treatment effects and transient effects from long-term sequelae. In this report, neuropsychological test performance is compared at baseline and 1 year postdiagnosis between 19 leukemia patients who received central nervous system and systemic chemotherapy and 19 patients who received only systemic chemotherapy. Patients were evaluated with a comprehensive test battery developed for children to assess general intelligence, memory, language, academic achievement, and visual-spatial and constructional, tactile-perceptual, and fine-motor skills. No significant treatment group, time, or interaction effects were obtained for higher order cognitive abilities (intelligence, memory, language, academic achievement). Mean scores for both groups on these measures were within the normal range. Significant treatment group effects were obtained on tasks requiring fine-motor and tactile-perceptual skills. An interaction effect was noted on the tactile-perceptual test, in which the performace of one group improved, while that of the other group declined. Results are discussed in relation to the preservation of higher order cofnitive abilities and the peripheral effects of systemically administered chemotherapies.

Key words: children; cancer; CNS; neuropsychology.


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 International Journal of Behavioral DevelopmentHome page
P. Robaey, P. Dobkin, J.-M. Leclerc, F. Cyr, C. Sauerwein, and Y. Theoret
A comprehensive model of the development of mental handicap in children treated for acute lymphoblastic leukaemia: A synthesis of the literature
International Journal of Behavioral Development, March 1, 2000; 24(1): 44 - 58.
[Abstract] [PDF]

Home page
 J Pediatr PsycholHome page
E. Raymond-Speden, G. Tripp, B. Lawrence, and D. Holdaway
Intellectual, Neuropsychological, and Academic Functioning in Long-Term Survivors of Leukemia
J. Pediatr. Psychol., March 1, 2000; 25(2): 59 - 68.
[Abstract] [Full Text] [PDF]


Disclaimer:
Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.