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Journal of Pediatric Psychology 15(4) pp. 459-475, 1990
© 1990 Society of Pediatric Psychology

other

Adherence Issues in Pediatric Bone Marrow Transplantation

Sean Phipps1 and Sydnee DeCuir-Whalley

Children's Hospital of Los Angeles

1 All correspondence should be sent to Sean Phipps, Department of Psychology, St. Jude Children's Research Hospital 332 N. Lauderdale, P.O. Box 318, Memphis, Tennessee 38101

The procedure of bone marrow transplantation entails a prolonged, aversive regimen in which adherence problems often develop, particularly with administration of oral antibiotic medications. A retrospective chart review revealed that 52% of pediatric patients evidenced significant adherence problems during the procedure. The highest rates of noncompliance were found in preschool and school-age children, with a surprisingly lower frequency in adolescents. Case summaries are presented to illustrate significant clincial issues and intervention strategies. These are discussed in terms of both their practical and theroretical significance regarding the determinants of adherence behavior.

Key words: bone marrow transplant; childhood leukemia; chronic illness; adherence; compliance; oral medication.


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