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Journal of Pediatric Psychology 19(6) pp. 779-790, 1994
© 1994 Society of Pediatric Psychology

research-article

Behavioral Phenotype in Children with Turner Syndrome1

Joanne Rovet2 and Lindsay Ireland

The Hospital for Sick Children Toronto

2All correspondence should be sent to Joanne Rovet, Psychology Department, The Hospital for Sick Children, 555 University Avenue, Toronto, Ontario, Canada M5G1X8

Compared Child Behavior Checklist results in 103 girls with Turner syndrome (TS) ages 7 to 13 years and 52 age-matched normal girls. Subjects with TS were part of a national study in Canada to evaluate growth hormone therapy in TS. Present data were obtained at baseline. Girls with TS scored below the comparison group in Total Social Competence (p < .0001), and above it in Total Behavior Problems (p < .05). Social (p < .0001). and Attention Problems (p < .001) scales. Item analysis revealed that subjects with TS were more immature, hyperactive, and nervous, and had poorer peer relations, greater difficulty at schooling, and more problems concentrating. In children with TS, height was correlated with social competence while karyotypes involving structural abnormalities of the X chromosome were associated with more behavior problems than a missing X or mosaicism.

Key words: behavior problems; Turner syndrom; children.


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