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Journal of Pediatric Psychology 21(6) pp. 833-840, 1996
© 1996 Society of Pediatric Psychology

research-article

Effect of Prenatal Alcohol and Cigarette Exposure on Two- and Six-Month-Old Infants' Adrenocortical Reactivity to Stress1

Douglas S. Ramsay, Margaret I. Bendersky and Michael Lewis2

Institute for the Study of Child Development, Robert Wood Johnson Medical School

2All correspondence should be addressed to Michael Lewis, Institute for the Study of Child Development, Department of Pediatrics. Robert Wood Johnson Medical School, University of Medicine and Dentistry of New Jersey, 97 Paterson Street, New Brunswick, New Jersey 08903-0019

Examined the effect of prenatal alcohol and cigarette exposure on infant adrenocortical reactivity to stress at 2 and 6 months of age. Cortisol response (pre-to poststressor increase) at 2 months was lower for the exposed than nonexposed infants, whereas cortisol response at 6 months did not differ between the exposed and nonexposed infants. The 2-month group difference in cortisol response reflected a higher prestressor cortisol level in the exposed infants.

Key words: adrenocortical reactivity; alcohol; cigarettes; cortisol; inoculation; prenatal exposure.


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