Journal of Pediatric Psychiatry, Vol 24, 511-514, Copyright © 1999 by Society of Pediatric Psychology
ME Schuler and P Nair
OBJECTIVE: To examine the effects of frequency of prenatal maternal cocaine
use on infant neurobehavioral outcome beyond the immediate postpartum
period, controlling for other substance use. METHODS: At 2 weeks
postpartum, the Brazelton Neonatal Behavioral Assessment Scale (BNBAS) was
administered to infants (N = 55) and their mothers were asked about their
prenatal drug use. Mother/infant dyads were placed in one of two groups
based on the number of days of reported cocaine use during pregnancy: high
frequency (n = 23, > 75th percentile reported days of use) or low
frequency (n = 32, < 75th percentile). RESULTS: Infants in the high
frequency cocaine group had worse BNBAS excitability scores than infants in
the low frequency cocaine group, when other substance use was controlled
statistically. CONCLUSIONS: High frequency of maternal cocaine use during
pregnancy is associated with poorer infant neurobehavioral outcome beyond
the early postpartum period, when other substance use is controlled.
ARTICLE
Brief report: frequency of maternal cocaine use during pregnancy and infant neurobehavioral outcome
Department of Pediatrics, University of Maryland School of Medicine, Baltimore 21201, USA. mschuler@pediatrics
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