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Journal of Pediatric Psychology 8(4) pp. 345-357, 1983
© 1983 Society of Pediatric Psychology

research-article

A Large-Sample Many-Variable Study of Motor Dysfunction of Infancy1

Patricia H. Ellison2, Carol Browning and John L. Horn

Department of Neurology and Pediatrics, The Medical College of Wisconsin Milwaukee, University of Denver

2All correspondence should be addressed to Patricia H. Ellison, NIH Senior Research Fellow, University of Denver, 2030 S. York Street, Denver, Colorado 80208.

We examined the relationship between a large number of variables and motor dysfunction of infancy (MDI) for 999 infants treated in the neonatal intensive care units of the Medical College of Wisconsin. Only three single variables were associated with significant increased risk of MDI: birth weight < 750 grams, intracranial bleeding (for spastic infants only), and hydrocephalus. Multivariate analyses, particularly factor analysis, better characterized variables preceding MDI. The first five factors were Factor I (31% variance): low birth weight, apnea, patent ductus arteriosus, and use of CPAP or respirator; Factor II (15% variance): maternal bleeding, respiratory distress syndrome, intubation, use of respirator, chest tube, and oxygen over 60%; Factor III (13% variance): intracranial bleed and hydro-cephalus; Factor IV (10% variance): single birth, low Apgar, and neonatal seizures; and Factor V (9% variance): black race and infant born in the hospital with the neonatal ICU.

Key words: Infancy; motor dysfunction; Apgar scores; seizures.


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