Skip Navigation


Journal of Pediatric Psychology Advance Access first published online on December 12, 2008
This version published online on April 2, 2009
Journal of Pediatric Psychology, doi:10.1093/jpepsy/jsn129
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow All Versions of this Article:
34/8/827    most recent
jsn129v2
jsn129v1
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrowRequest Permissions
Right arrow Disclaimer
Google Scholar
Right arrow Articles by Roberts, J. E.
Right arrow Articles by Bailey, D. B.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Roberts, J. E.
Right arrow Articles by Bailey, D. B., Jr
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

© The Author 2008. Published by Oxford University Press on behalf of the Society of Pediatric Psychology. All rights reserved. For permissions, please e-mail: journals.permissions@oxfordjournals.org

Trajectories and Predictors of the Development of Very Young Boys with Fragile X Syndrome

Jane E. Roberts, PhD1, Jean B. Mankowski, PhD1, John Sideris, PhD1, Barbara Davis Goldman, PhD1,2, Deborah D. Hatton, PhD1, Penny L. Mirrett, PhD1, Grace T. Baranek, PhD3, J. Steven Reznick, PhD2, Anna C. J. Long, BA1 and Donald B. Bailey, Jr, PhD4

1FPG Child Development Institute, The University of North Carolina at Chapel Hill, 2Department of Psychology, The University of North Carolina at Chapel Hill, 3Division of Occupational Science, Department of Allied Health Sciences, The University of North Carolina at Chapel Hill, and 4RTI International

All correspondence concerning this article should be addressed to Jane E. Roberts, PhD, Department of Psychology, University of South Carolina, Barnwell College, Columbia, SC 29208, USA. E-mail: jane.roberts{at}sc.edu


  Abstract

Objective To describe the development of young boys with fragile X syndrome (FXS). Methods Fifty-five boys (aged 8–48 months at study entry) with the full mutation FXS received multiple developmental assessments. Results As expected, the boys’ rate of development was significantly lower than chronological age expectations. No evidence of slowing in the rate of development was found. Autistic behavior was negatively associated with development, but maternal IQ was not. Developmental delays were evident in some domains as early as 9 months; however, initial detection of delays is complicated by measures and criteria used. Developmental age scores at 31 months of age were related to scores obtained at 61 months of age only in the global composite and visual reception domain. Conclusions Developmental delays are evident in some infants with FXS as young as 9 months of age. Pediatric psychologists need to be informed about the developmental profiles in young children with FXS to accurately diagnose, treat, and support these children and their families.

Key words: cognitive development; fmr1; fragile X.

Received June 6, 2008; revision received November 11, 2008; accepted November 11, 2008


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?




Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.