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Journal of Pediatric Psychology Advance Access published online on August 26, 2009
Journal of Pediatric Psychology, doi:10.1093/jpepsy/jsp073
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© The Author 2009. Published by Oxford University Press on behalf of the Society of Pediatric Psychology. All rights reserved. For permissions, please e-mail: journals.permissions@oxfordjournals.org

Treatment Adherence Impact: The Systematic Assessment and Quantification of the Impact of Treatment Adherence on Pediatric Medical and Psychological Outcomes

Ahna LH Pai, PhD1 and Dennis Drotar, PhD2

1Center for the Promotion of Adherence and Self-Management Division of Behavioral Medicine and Clinical Psychology, Cincinnati Children's Hospital Medical Center and 2Department of Pediatrics, University of Cincinnati College of Medicine

All correspondence concerning this article should be addressed to Ahna L.H. Pai, PhD, Cincinnati Children's Hospital Medical Center, 3333 Burnet Avenue, MLC 7039, Cincinnati, OH 45229, USA. E-mail: ahna.pai{at}cchmc.org


  Abstract

Objective Treatment adherence impact (TAI) is the quantification of the effects of adherence behaviors on medical or psychological outcomes using systematic assessment and analytic methods. The purpose of this review is to provide a framework for the measurement and analysis of TAI. Methods Specific studies were selected from the treatment adherence literature to illustrate methods to assess TAI. Results There are many methods available to investigators to evaluate TAI and, when possible, multiple impact outcomes should be included in adherence studies. The methods available to assess TAI and barriers to assessing TAI vary across illness group requiring illness-specific applications of the concepts presented. Conclusions Systematically examining TAI in adherence studies could advance the state of the art of treatment adherence science.

Key words: treatment adherence; chronic illness; pediatric; assessment..

Received January 14, 2009; revision received July 20, 2009; accepted July 22, 2009


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