Journal of Pediatric Psychology, Vol. 27, No. 1, 2002, pp. 37-45
© 2002 Society of Pediatric Psychology
Methodological Issues in Outcome Studies of At-Risk Infants
School of Medicine, Southern Illinois University
All correspondence should be sent to Glen P. Aylward, SIU School of Medicine, Dept. of Pediatrics, P.O. Box 19658, Springfield, Illinois 62794-9658. E-mail: gaylward{at}siumed.edu .
Objective: To identify methodologic problems found in follow-up studies of infants at biologic and environmental risk and provide solutions and recommendations.
Methods: This article is a literature review.
Results: Problems fall into four groupings: (1) conceptualization/design issues, 2) subject population concerns, 3) procedural issues, and 4) measurement/outcome concerns.
Conclusions: Main-effect models are not useful; confounding and mediating variables must be identified. In addition, the following are needed: alternative analytic techniques, more precise subject selection and characterization of risk factors, geographically defined samples, broadened scope of outcome measures, and use of epidemiologic techniques.
Key words: developmental outcome; follow-up; high risk; infants; methodology.
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