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Journal of Pediatric Psychology Advance Access published online on March 9, 2005
Journal of Pediatric Psychology, doi:10.1093/jpepsy/jsj013
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Journal of Pediatric Psychology © The Author 2005. Published by Oxford University Press on behalf of the Society of Pediatric Psychology. All rights reserved. For permissions, please e-mail: journals.permissions@oupjournals.org
Received November 28, 2004
Revised February 2, 2005
Accepted February 8, 2005

Article

Identifying, Recruiting, and Enrolling Adolescent Survivors of Childhood Cancer into a Randomized Controlled Trial of Health Promotion: Preliminary Experiences in the Survivor Health and Resilience Education (SHARE) Program

Kenneth P. Tercyak PhD1*, Jessica R. Donze MPH, RD1, Sowmya Prahlad MS1, Revonda B. Mosher RN, MSN, CPNP2, and Aziza T. Shad MD1

1 Lombardi Comprehensive Cancer Center, Georgetown University Medical Center and
2 Center for Cancer and Blood Disorders, Children’s National Medical Center

* To whom correspondence should be addressed.
Kenneth P. Tercyak, E-mail: tercyakk{at}georgetown.edu


  Abstract

Objective To report on the identification, recruitment, and enrollment of adolescent survivors of childhood cancer into an ongoing randomized controlled trial (RCT) of health promotion. Methods A total of 244 adolescents were contacted by mail and telephone to assess their trial eligibility. Data were collected with respect to each adolescent’s demographics and trial recruitment efforts (frequency and intensity of telephone call contact); exclusion and randomization status were tracked throughout. Results Thirty-one percent of adolescents were ultimately randomized in the trial and 69% were excluded from randomization (13% were ineligible, 33% refused to participate, 22% were unreachable or nonresponsive, that is, did not respond to trial mailings or telephone calls, and less than 1% were withdrawn prior to randomization). Among all eligible adolescents, the trial’s consent rate was 49%. Adolescents excluded owing to refusal resided the farthest away from the intervention site and experienced the least amount of telephone call contact time. The primary reasons for trial refusal were lack of interest in health promotion (28%) and lack of time to participate (23%). Conclusions Health promotion RCTs among adolescent survivors of childhood cancer may help prevent and control the onset and severity cancer-treatment-related late effects. However, trial success may be contingent upon tracing nonresponsive adolescents and reducing and eliminating barriers to participation.

Keywords: cancer survivorship; health behavior; health promotion; randomized controlled trial.
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