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Journal of Pediatric Psychology Advance Access published online on May 4, 2005
Journal of Pediatric Psychology, doi:10.1093/jpepsy/jsj014
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Journal of Pediatric Psychology © The Author 2005. Published by Oxford University Press on behalf of the Society of Pediatric Psychology. All rights reserved. For permissions, please e-mail: journals.permissions@oupjournals.org
Received April 19, 2004
Revised February 1, 2005
Accepted February 9, 2005

Article

The Impact on Health-Related Quality of Life from Non-Steroidal Anti-Inflammatory Drugs, Methotrexate, or Steroids in Treatment for Juvenile Idiopathic Arthritis

Russ Riddle MS1*, Christina N. Ryser PhD2, Anne A. Morton PhD1, J. D. Sampson MA1, Richard H. Browne PhD1, Marilynn G. Punaro MD2, and Robert J. Gatchel PhD3

1 Texas Scottish Rite Hospital for Children
2 Texas Scottish Rite Hospital for Children; The University of Texas Southwestern Medical Center at Dallas
3 The University of Texas Southwestern Medical Center at Dallas

* To whom correspondence should be addressed.
Russ Riddle, E-mail: russ.riddle{at}tsrh.org


  Abstract

Objective To assess and compare the impact of medication treatments on health-related quality of life (HRQOL), family function, and medical status in children with juvenile idiopathic arthritis (JIA). Methods Fifty-seven children diagnosed with JIA were assessed by a pediatric rheumatologist and placed into one of three treatment groups: (1) non-steroidal anti-inflammatory; (2) methotrexate; or (3) steroids via IV methylprednisolone. Questionnaires were administered at baseline and 4-month follow-up. The attending pediatric rheumatologist provided additional medical information. Results Data document the impact of JIA on HRQOL, particularly on physical and pain domains. Steroid patients experienced improved HRQOL at follow-up relative to other groups, despite reporting more problems with side effects. Conclusion These results demonstrate positive benefits of steroids in treating JIA children, despite the greatest incidence of adverse side effects.

Keywords: health-related quality of life; juvenile arthritis; outcomes.
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 The Journal of RheumatologyHome page
S. RINGOLD, C. A. WALLACE, and F. P. RIVARA
Health-Related Quality of Life, Physical Function, Fatigue, and Disease Activity in Children with Established Polyarticular Juvenile Idiopathic Arthritis
J Rheumatol, June 1, 2009; 36(6): 1330 - 1336.
[Abstract] [Full Text] [PDF]


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