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Journal of Pediatric Psychology Advance Access published online on July 20, 2006
Journal of Pediatric Psychology, doi:10.1093/jpepsy/jsj062
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© The Author 2005. Published by Oxford University Press on behalf of the Society of Pediatric Psychology. All rights reserved. For permissions, please e-mail: journals.permissions@oupjournals.org
Received April 5, 2004
Revised November 9, 2004
Accepted November 10, 2004

Article

Validation of a Symptom Provocation Test for Laboratory Studies of Abdominal Pain and Discomfort in Children and Adolescents

Lynn S. Walker PhD 1 *, Sara E. Williams MS 1, Craig A. Smith PhD 1, Judy Garber PhD 1, Deborah A. Van Slyke PhD 1, Tricia Lipani MS 1, John W. Greene MD 1, Howard Mertz MD 1, and Bruce D. Naliboff PhD 2

1 Vanderbilt University Medical Center
2 University of California at Los Angeles

* To whom correspondence should be addressed.
Lynn S. Walker, E-mail: lynn.walker{at}vanderbilt.edu


  Abstract

Objective Assessed the convergent and discriminant validity of a water load symptom provocation test (WL-SPT) in creating visceral sensations similar to the naturally occurring sensations experienced by children with functional abdominal pain. Methods Participants were pediatric patients with functional abdominal pain (N = 110) and healthy school children (N = 120) between the ages of 8 and 16 years. Pain patients completed questionnaires describing gastrointestinal (GI) and nongastrointestinal (non-GI) symptoms associated with their typical abdominal pain episodes. Weeks later, the WL-SPT was administered to pain patients and well children. Before and immediately following the WL-SPT, children rated their symptoms. Results The WL-SPT produced (a) significant increases in children’s GI symptoms that were reliably predicted by the children’s naturally occurring GI symptoms, and (b) significantly greater increases in GI symptoms in pain patients than in well children. Conclusions The WL-SPT produces clinically relevant symptoms for laboratory studies of children with functional abdominal pain.

Keywords: children; functional abdominal pain; pain perception; recurrent abdominal pain; visceral hypersensitivity.
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