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Journal of Pediatric Psychology Advance Access published online on March 2, 2006

Journal of Pediatric Psychology, doi:10.1093/jpepsy/jsj109
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© The Author 2006. Published by Oxford University Press on behalf of the Society of Pediatric Psychology. All rights reserved. For permissions, please e-mail: journals.permissions@oxfordjournals.org
Received June 22, 2005
Revised January 31, 2006
Accepted February 9, 2006

Article

A Meta-Analysis of the Effects of Psychological Interventions in Pediatric Oncology on Outcomes of Psychological Distress and Adjustment

Ahna L.H. Pai PhD 1 *, Dennis Drotar PhD 1, Kathy Zebracki MA 2, Melisa Moore MA 2, and Eric Youngstrom PhD 2

1 Rainbow Babies and Children’s Hospital, Case Western Reserve University School of Medicine
2 Case Western Reserve University

* To whom correspondence should be addressed.
Ahna L.H. Pai, E-mail: paia{at}email.chop.edu


   Abstract

Objective To estimate the effectiveness of psychological interventions in pediatric oncology on decreasing psychological distress and increasing psychological adjustment using meta-analytic methods. Methods A meta-analysis was conducted on 12 psychological intervention studies in pediatric oncology using a weighted least squares (WLS) approach and random effect models. Results Effect sizes significantly different from zero were found for parent distress (mean = 0.35, 95% CI = 0.20-0.49, n = 7) and parent adjustment (mean = 0.23, 95% CI = 0.07-0.40, n = 5). Effect sizes for child distress, child adjustment, parent-reported child distress, and parent-reported child adjustment were not significantly different from zero. Conclusions Psychological interventions in pediatric oncology show promise in decreasing distress and improving the adjustment of parents of children with cancer but may have minimal effects for child outcomes. Methodological issues of intervention research are discussed.

Keywords: cancer; intervention; pediatric oncology; psychological adjustment; psychological distress.
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