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Journal of Pediatric Psychology Advance Access published online on May 4, 2006

Journal of Pediatric Psychology, doi:10.1093/jpepsy/jsj116
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© The Author 2006. Published by Oxford University Press on behalf of the Society of Pediatric Psychology. All rights reserved. For permissions, please e-mail: journals.permissions@oxfordjournals.org
Received April 28, 2005
Revised March 11, 2006
Accepted March 20, 2006

Article

Family Mediators and Moderators of Treatment Outcomes Among Youths with Poorly Controlled Type 1 Diabetes: Results From a Randomized Controlled Trial

Deborah A. Ellis PhD 1 *, Justin Yopp PhD 2, Thomas Templin PhD 3, Sylvie Naar-King PhD 4, Maureen A. Frey RN, PhD 4, Phillippe B. Cunningham PhD 5, April Idalski MSW 1, and Larissa N. Niec PhD 6

1 Department of Psychiatry and Behavioral Neurosciences, Wayne State University
2 Columbus Children’s Hospital
3 School of Nursing, Wayne State University
4 Carman and Ann Adams Department of Pediatrics, Wayne State University
5 Department of Psychiatry, Medical University of South Carolina
6 Department of Psychology, Central Michigan University

* To whom correspondence should be addressed.
Deborah A. Ellis, E-mail: dellis{at}med.wayne.edu


   Abstract

Objective To determine whether multisystemic therapy (MST) improved family relationships among youths with poorly controlled type 1 diabetes and whether these changes mediated MST effects on health outcomes. The moderating effect of family demographics on study outcomes was also assessed. Methods A randomized controlled trial was conducted with 127 youths. Changes in general family relationships and caregiver support for diabetes care from baseline to treatment completion were assessed. Structural equation modeling (SEM) was used to test whether changes in family relations mediated improvements in frequency of blood glucose testing (BGT) and metabolic control. Results MST increased support for diabetes care from both primary and secondary caregivers in two-parent but not in single-parent families. However, MST had the strongest effects on BGT and metabolic control in single-parent families. SEM did not support family relations as the mediator of improved BGT or metabolic control. Rather, MST had a direct effect on BGT for all participants. BGT mediated improvements in metabolic control among single-parent families. Conclusions MST improved family relationships for youths with diabetes in two-parent but not in single-parent families. Objective outcomes related to diabetes were strongest for single-parent families. Other processes such as increased parental monitoring may have been responsible for improved health outcomes among these families.

Keywords: diabetes; family functioning; multisystemic therapy.
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