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Journal of Pediatric Psychology Advance Access first published online on May 23, 2007
This version published online on May 24, 2007
Journal of Pediatric Psychology, doi:10.1093/jpepsy/jsm030
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© The Author 2007. Published by Oxford University Press on behalf of the Society of Pediatric Psychology. All rights reserved. For permissions, please e-mail: journals.permissions@oxfordjournals.org

Identifying Barriers to Medication Adherence in Adolescent Transplant Recipients

Laura E. Simons, Phd1 and Ronald L. Blount, Phd2

1Childrens Hospital Boston2University of Georgia

All correspondence concerning this article should be addressed to Laura Simons, PhD, Center for Anxiety and Related Disorders at Boston University, 648 Beacon Street, 6th Floor, Boston, Massachusetts 02215. E-mail: laura.simons{at}childrens.harvard.edu, lauraesimons{at}gmail.com


  Abstract

Objective To create Parent and Adolescent Medication Barriers Scales (PMBS and AMBS) for assessing perceived barriers to medication adherence in adolescent transplant recipients. Methods These scales were developed and initially validated with 78 families. Participants responded to questions concerning perceived barriers to medication adherence. To assess validity, data on contextual factors (e.g., family functioning) and adherence measures were collected. Results A principal components factor analysis resulted in the following subscales for the PMBS and AMBS: (a) Disease Frustration/Adolescent Issues, (b) Regimen Adaptation/Cognitive Issues, (c) Ingestion Issues, and (d) Parent Reminder (PMBS only). Significant associations were found between barrier scale scores, contextual factors, and adherence. Conclusions The PMBS and AMBS are brief and psychometrically promising scales for assessing perceived barriers to adherence in adolescent transplant recipients.

Key words: adherence; adolescent; measurement; medication; pediatric transplant.

Received October 6, 2006; revision received January 21, 2007; accepted March 26, 2007


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