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Journal of Pediatric Psychology Advance Access published online on December 3, 2007
Journal of Pediatric Psychology, doi:10.1093/jpepsy/jsm106
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© The Author 2007. Published by Oxford University Press on behalf of the Society of Pediatric Psychology. All rights reserved. For permissions, please e-mail: journals.permissions@oxfordjournals.org

Acute Impact of Immediate Release Methylphenidate Administered Three Times a Day on Sleep in Children with Attention-Deficit/Hyperactivity Disorder

Penny Corkum, PhD1, Rachel Panton, MA2,{ddagger}, Sarah Ironside, BSc1,{dagger}, Marilyn MacPherson, MD3 and Tracey Williams, MD3

1Dalhousie University, 2Mount Saint Vincent University, and 3Truro Pediatrics, Colchester Regional Hospital

All correspondence concerning this article should be addressed to: Dr Penny Corkum, Department of Psychology, Dalhousie University, Halifax, Nova Scotia, Canada, B3H 4J1. E-mail: penny.corkum{at}dal.ca


  Abstract

Objective To determine the impact of immediate release Ritalin, given three times a day, on sleep quality and quantity in medication-naïve, newly diagnosed children with attention-deficit/hyperactivity disorder (ADHD). Methods Children (aged 6–12) rigorously diagnosed with ADHD (n = 21) underwent multiple measurement assessments (i.e., actigraphy, sleep diary, and questionnaires) during a 1-week baseline and then during a 3-week blinded randomized medication trial. Results Although the medication was effective in reducing ADHD symptoms, analyses of actigraphy and sleep diary data found statistically and clinically significant changes in the children's total sleep time and sleep onset latency in the medication compared to the no medication conditions. No effects on sleep were found based on the sleep questionnaire. Conclusions Physicians and parents are encouraged to closely monitor children's sleep when treating ADHD with stimulant medication.

Key words: ADHD; children; medication; sleep.

{dagger}Sarah Ironside is now a medical student at Dalhousie University.

{ddagger}Rachel Panton is now a psychologist (Candidate Register) with the Colchester East Hants ADHD Clinic.

Received June 4, 2007; revision received August 18, 2007; accepted October 9, 2007


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